Numbing cream 4% lidocaine is used to numb the skin. It used to numb the skin for a variety of uses. Some of those uses include:
This medicine contains the active ingredient lidocaine hydrochloride (previously known as lignocaine hydrochloride in the UK).
Lidocaine is a type of medicine called a local anaesthetic. It is used to numb areas that would otherwise feel pain.
Pain is caused by the stimulation of pain receptors at the ends of nerves. The stimulation causes sodium to enter the nerve ending, which causes an electrical signal to build up in the nerve. When this electrical signal is big enough, it passes along the nerve to the brain, where the signal is interpreted as pain.
Lidocaine works by temporarily blocking this pathway of pain signals along nerves. It does this by stopping the sodium entering the nerve ending at the site of the pain. This prevents an electrical signal building up and passing along the nerve fibers to the brain.
The way numbing cream 4% lidocaine cream works is by transferring the active ingredient, lidocaine, into the skin where it temporarily affects the nerves.
In order to get the active ingredient into the skin, the formulation should include skin penetration enhancers also known as drivers.
Some of the more commonly known safe and effective drivers are:
Any single or combination of two or more of these drivers added to the formulation of numbing cream 4% lidocaine will temporarily improve the penetration capability of the active ingredient in numbing cream 4% entering the skin where the nerves that signal pain are located.
NeuroMed 7 Single-use, sanitary 4 mL packets – lidocaine – smooth and creamy grit free formula – supplied in single-use sanitary packets – includes penetration enhancers in its formulation