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The Best Topical Lidocaine Cream

Question mark over a lidocaine cream bottle

The best topical lidocaine cream has advantages that the others do not. The advantages that you may look for in the best topical lidocaine cream may be based on price, fast onset of action, therapeutic efficacy, safety, ease of use or maybe some other factors that best suit your needs.

Many products that suppliers claim make them the best topical lidocaine cream come in the form of, “formulated just for tattoos,” or “made for laser hair removal,” or other such unusual and meaningless comments. The reason why these claims as the best topical lidocaine cream for this or that are meaningless is that all effective lidocaine creams use the same active pharmaceutical ingredient (API), which is LIDOCAINE. Lidocaine and the other “caine” API’s all work about the same way (called the mechanism of action). They get into a part of the nerve conduction process called the high voltage sodium ion channel. When a painful effect occurs in an area, the nerve signals that pain by allowing sodium to enter this channel which in turn starts a process that sends the pain signal to the brain. The lidocaine simply enters this channel and blocks the potential for the nerve to activate and send pain (or other discomfort signals) to the brain.

What Makes a Lidocaine Cream Better?

Here are some of the main factors to consider while evaluating lidocaine cream products:


  • Quickest onset of action (how fast it takes before it adequately numbs the skin)
  • Lasting effect (does it last through the length of you want or need?)
  • Safety (what are the safety features of the product – if misused, even the best topical lidocaine numbing cream has a risk of causing serious health issues)
  • Is it priced fairly? (when including price as a factor, always compare gram to gram (mL to mL). Some marketers like to trick their prospects into thinking their products are a good price by only selling small one ounce (28 grams by weight, 30 mL by volume) at a price that seems low when in fact if compared to other products in larger containers may be much higher when compared gram to gram.

NeruoMed 7 Lidocaine Cream

NeuroMed 7 is shown in an approved study to not enter the blood stream in its intact form. This means that it did not create the problem that causes toxicity (poisoning). This is very important especially when using over surface areas that are not very small or when using more than once consistently. This is NOT to suggest at all that it is ok to abuse the NeuroMed 7 cream. All of these products, even the best topical lidocaine cream should always be used as directed and in a responsible manner. This means to NOT use it on large areas and do not use it too frequently or on a consistent basis over a prolonged period of time. When using even the best topical lidocaine cream, such as NeuroMed 7, make sure to speak with your doctor about it prior to using, especially if you are unsure how much to use, how often to use, or on what size area to use it. 

Advantages of NeuroMed Brand Products:

  • Single-use, sanitary packets to decrease risk of cross contamination
  • Metered dose packaging to improve precision and reduce wastage
  • Proprietary formulation to improve onset time and efficacy
  • Proprietary formulation to reduce risk of systemic entry
  • Multiple package size options for improved clinical flexibility and minimization of wastage
  • Competitive pricing

Single-Use Lidocaine Cream Packets

numbing cream for chemo therapy

An important safety feature that the NeuroMed Brand creators included to make them the best topical lidocaine numbing cream products is the unique, single-use, sanitary packets packaging. This packaging was created in order to reduce the risk of cross contamination inherent with the use of multi-use containers, particularly, jars. Each time a multi-use container is opened, the risk of toxins and/or microbes entering the container is increased. This can lead to an ever-increasing risk of adverse outcomes due to contamination, especially if the formulators of products contained in multi-use packaging included skin penetrating drivers used to improve delivery of the lidocaine into the skin. These potential contaminants can also be carried into the skin in these cases.

Lidocaine in BLT Cream

There are many topical lidocaine cream options available. NeuroMed BLT Combination Package includes all three of the most commonly used topical anesthetics used by clinicians. In fact, the compounded topical anesthetic version most commonly used in aesthetic procedures is known as “BLT.” Compounded BLT requires single prescriptions per each patient in order to maintain compliance. NeuroMed BLT provides a supply of each, allowing for significant flexibility not seen with any other of the lidocaine options currently available anywhere in the marketplace.


When searching for the best lidocaine cream options, always compare to NeuroMed BLT Combination Package. NeruoMed BLT is the best solution in for clinical use flexibility, rapid onset, safety and efficacy. The unique packaging and proprietary formulation make NeuroMed BLT the best topical numbing cream choice.

Cost of Lidocaine Cream

When comparing cost of the best topical lidocaine cream products, always pay attention to the cost per gram (or milliliter – mL – if by volume – 1 gram = 1 mL with these products). Many crafty marketers sell small containers so it looks like they are a better price. This is a hidden way of taking advantage of people who are busy and not always able to pay attention to details like this that matter when trying to conserve money and make a good choice.

Lidocaine Cream Onset Time

How fast can Lidcoaine Cream numb the skin? It depends on how it’s formulated and applied. There are various physical and chemical wasys to affect how quickly lidocaine cream numbs the sknin. Physical means can include the use of heat, ultrasound and laser. Another physical method can be applying the anesthetic after removal of the stratum corneum (top, barrier layer of skin) using tape stripping. Each of these physical methods have been shown to speed the rate at which a topical anesthetic penetrates the skin and starts its action. However, each requires potentially costly equipment. In an effort to improve the onset of action in order to make the best topical lidocaine numbing cream, some makers add chemical drivers.


The most commonly accepted safe and effective drivers are:

  • ethoxydiglycol
  • MSM
  • Propylene glycol
  • Urea
  • Isopropyl miristate
  • liposomes (nano-particles that are essentially fatty bubbles that encompass the anesthetic molecules)

In order for the best topical lidocaine numbing cream products to be most effective in these terms, it is important that the formulation include one or more of these chemical drivers to enhance penetration capability potential. All NeuroMed Brand Topical Anesthetic products include three of these important drivers in their formulations. This is one of the many factors that Sambria Pharmaceuticals included in its formulation strategy when creating NeuroMed 7 and the products contained in the NeuroMed BLT Combination Package.